更新時(shí)間:2016-06-09
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鳥苷-5′-三磷酸鈉鹽
GTP, Trisodium Salt
Cas 號(hào): 【36051-31-7】 M D L: MFCD00077781
鳥苷-5′-三磷酸鈉鹽分子式: C10H13N5O14P3Na3 分子量: 589.13
別 名: 5’-三磷酸鳥苷三鈉
Guanosine 5′-triphosphate sodium salt hydrate
GTP
Guanosine 5′-triphosphate (GTP), trisodium salt
鳥苷-5′-三磷酸鈉鹽 ≥95% (HPLC) 10mg
鳥苷-5′-三磷酸鈉鹽 ≥95% (HPLC) 25mg
性 狀: 白色粉末,易溶于水,不溶于乙醇。在PH1條件下A250/A260 =0.96±0.05; A280/A260 =0.67±0.03; λmax=256±1nm
質(zhì)量標(biāo)準(zhǔn): 外觀Appearance 白色粉末
紅外光譜鑒別Infrared spectrometry Conforms
純度Purity ≥95.0% (HPLC)
溶劑Solvent ≤4%(GC)
Em (252nm, 0.01N HCl) >10000
鑒別試驗(yàn)Identification(P/F) 合格
水分Moisture ) ≤9%(K.F)
鈉Sodium 10.5 ~ 14.5% by ICP Atomic emission
貯 存: -20℃保存
用途 GTP 是作為磷酸鹽和焦磷酸鹽的載體把通道化學(xué)能量帶進(jìn)專一的合成路徑中, GTP 激活信號(hào)傳導(dǎo)G蛋白,后者涉及到各種各樣的細(xì)胞程序包括增殖、分化和激活幾種細(xì)胞內(nèi)的具級(jí)聯(lián)效益的激酶。 增殖和凋亡部分由GTP的水解調(diào)控,小型Ras 和 Rho GTP激酶控制GTP的水解。
另外,在信號(hào)傳導(dǎo)中,GTP 在酶合成DNA和RNA時(shí)也作為單核苷酸的高能前提物
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